Infectious canine hepatitis

Clinical Signs

Systemic

Pyrexia (Fever) Required Depression Required Anorexia Required

General Systemic Signs

Polydipsia Sudden death Specific

Respiratory

Nasal discharge Cough Pharyngitis Required

Ophthalmic

Corneal opacity Specific Conjunctivitis Required

Digestive

Vomiting Required Abdominal pain Pathognomonic

Hemolymphatic

Tonsillitis Required Cervical lymphadenomegaly Required

Nervous

Neurologic manifestation

Diagnosis

Virus isolation and identification

Fluorescent antibody test

Virus neutralization test

Hemagglutination inhibition test

Complement fixation test

Detection of intranuclear inclusion bodies

Alanine aminotransferase measurement

Complete blood count

Treatment

Hepatitis antiserum administration

Combined hepatitis distemper antiserum administration

Glucose saline administration

Blood transfusion

Prevention & Control

Hygienic management

Detection of inapparent infections

Vaccination with modified live attenuated vaccine

Multivalent vaccination

Related Products

Trade Name	Dosage Form	Manufacturer	Action
Vanguard Plus 5/CV Canine Distemper, Adenovirus, Parainfluenza, Parvovirus, and Coronavirus Vaccine	N/A	Zoetis

Active Ingredients

Host Species

Dogs Primary host Susceptibility: High

Associated Microorganisms

Canine adenovirus type 1 Cause

Classification

Etiology Viral disease

Notifiable Yes

Transmissibility Moderate

Infectiousness Highly infectious

OIE Category Transboundary animal disease

Occurrence Patterns

Endemic, Epidemic

Disease Courses

Acute