Simparica Trio

سيمباريكا تريو

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Pharmaceutical Tablet

Simparica Trio (sarolaner, moxidectin, and pyrantel chewable tablets) is an all-in-one monthly oral parasiticide for dogs 8 weeks of age and older weighing 2.8 lbs or greater. Indicated for the prevention of heartworm disease (Dirofilaria immitis), treatment and control of tick infestations (5 tick species), treatment and prevention of flea infestations (Ctenocephalides felis), and treatment and control of roundworms and adult hookworms.

Dosage Form

Tablet

Product Type

Pharmaceutical

Manufacturer

Zoetis

Package

Cartons of 1, 3, or 6 flavored chewable tablets color-coded across 6 weight bands (2.8-5.5 lbs up to 88.1-132.0 lbs)

Dosages

Species Dosage Route Duration
Dog 1 chewable tablet per mouth monthly according to body weight Oral (PO) Once monthly year-round

Withdrawal Periods

No withdrawal information available.

Indications

  • Prevention of heartworm disease caused by Dirofilaria immitis.

  • Treatment and prevention of flea infestations (Ctenocephalides felis) for one month.

  • Treatment and control of tick infestations (Amblyomma americanum, Amblyomma maculatum, Dermacentor variabilis, Ixodes scapularis, Rhipicephalus sanguineus).

  • Treatment and control of roundworm (Toxocara canis, Toxascaris leonina) and hookworm (Ancylostoma caninum, Uncinaria stenocephala) infections.

Contraindications

  • Do not use in dogs less than 8 weeks of age or weighing less than 2.8 lbs (1.3 kg).

Precautions

  • Sarolaner is an isoxazoline; use with caution in dogs with a history of seizures or other neurologic disorders.

  • Prior to administration, dogs should be tested for existing heartworm infections.

Side Effects

  • Most common adverse reactions include vomiting, diarrhea, lethargy, anorexia, and polyuria/polydipsia.

Images

Documents

  • Simparica Trio Prescribing Information

    Leaflet
    Download

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