Perdef 2X Injectable suspension

بيرديف 2 إكس معلق للحقن (إيسوفلوبيريدون أسيتات)

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Pharmaceutical

Perdef 2X (isoflupredone acetate injectable suspension, 2 mg/mL) is a potent synthetic corticosteroid combining high glucocorticoid and mineralocorticoid activity (approximately 50 times the anti-inflammatory potency of hydrocortisone). Indicated for ketosis in dairy cows, musculoskeletal inflammation in horses and cattle, and acute hypersensitivity reactions.

Dosage Form

N/A

Product Type

Pharmaceutical

Manufacturer

Zoetis

Package

Vials of 100 mL multi-dose glass vials

Dosages

Species Dosage Route Duration
Cattle 10 to 20 mg (5 to 10 mL) per animal deep intramuscularly; repeat in 12 to 24 hours if needed Intramuscular (IM) 1 to 2 injections
Horse 5 to 20 mg (2.5 to 10 mL) intramuscularly or intrasynovially (1 to 5 mL per joint) Intramuscular (IM) or Intrasynovial As indicated clinically
Swine 5 mg (2.5 mL) per 150 kg body weight intramuscularly Intramuscular (IM) Single dose

Withdrawal Periods

Species Meat (days) Milk (days) Eggs (days)
Cattle 7 0
Swine 7

Indications

  • Treatment of bovine ketosis (acetonemia) in lactating dairy cattle.

  • Musculoskeletal conditions including arthritis, tendinitis, and bursitis in horses and cattle.

  • Supportive treatment of acute hypersensitivity reactions and endotoxic shock in swine and cattle.

Contraindications

  • Do not use in pregnant cattle during the last trimester (may induce premature parturition).

  • Contraindicated in animals with active viral or fungal corneal ulcers.

Precautions

  • Corticosteroids may suppress the immune response; concurrent antimicrobial therapy should be provided in presence of bacterial infection.

  • Mineralocorticoid activity may cause hypokalemia with repeated doses; monitor potassium levels.

Side Effects

  • Transient polyuria, polydipsia, and hypokalemia with high or repeated dosages.

Images

Documents

  • Perdef 2X Injectable suspension Prescribing Information

    Leaflet
    Download

Active Ingredients

Diseases

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