Leptospirosis

Clinical Signs

Systemic

Pyrexia (Fever) Required

General Systemic Signs

Inappetence (Anorexia) Stillbirth Icterus Pathognomonic

Reproductive

Abortion Specific Bloody milk Specific Flaccid udder

Ophthalmic

Lacrimation Photophobia Periodic ophthalmia

Respiratory

Dyspnea

Urinary

Hemoglobinuria Pathognomonic

Hemolymphatic

Acute hemolytic anemia Pathognomonic

Diagnosis

Dark field microscopy

Silver staining

Fluorescent antibody test

Guinea pig inoculation

Microscopic agglutination test

Treatment

Streptomycin

Tetracycline

Whole blood transfusion and intravenous fluids

Prevention & Control

Identify and eliminate carrier animals

Eliminate wet muddy environments

Rodent control

Multivalent vaccination

Related Products

Trade Name	Dosage Form	Manufacturer
Bovi-Shield GOLD FP 5 L5	N/A	Zoetis
FarrowSure Gold	N/A	Zoetis
Spirovac Bovine Leptospirosis Vaccine	N/A	Zoetis
Spirovac VL5 Bovine Vibriosis & Leptospirosis Vaccine	N/A	Zoetis
StayBred VL5 Bovine Reproductive Vaccine	N/A	Zoetis
Vanguard Plus 5 L4 CV Canine Multi-Antigen Vaccine	N/A	Zoetis
Liquamycin LA-200 (oxytetracycline injection 200 mg/mL)	N/A	Zoetis
CattleMaster 4 + VL5 Bovine Respiratory & Reproductive Vaccine	N/A	Zoetis
Aureomycin 50 Chlortetracycline Type A Medicated Article	N/A	Zoetis
Bovi-Shield GOLD FP 5 Cattle Vaccine	N/A	Zoetis
Parvo Shield L5 Swine Parvovirus and Leptospirosis Vaccine	N/A	Zoetis

Active Ingredients

Host Species

Cattle Primary host Susceptibility: High

Sheep Susceptibility: High

Goat Susceptibility: High

Horse Susceptibility: High

Pig Susceptibility: High

Dogs Susceptibility: High

Human Susceptibility: High

Associated Microorganisms

Leptospira interrogans Cause

Classification

Etiology Bacterial disease

Zoonotic Yes

Transmissibility Moderate

Infectiousness Moderately infectious

Occurrence Patterns

Endemic